Research

  • Kratom – Pharmacology, Clinical Implications, and Outlook: A Comprehensive Review

    Recent evidence has revealed that kratom has physiological effects similar to opioids, including pain relief and euphoria, as well as stimulant properties, which together raise potential concern for dependence and addiction.

  • Clinical Implications of Kratom (Mitragyna speciosa) Use: a Literature Review

    Kratom's potential as a therapeutic tool is under investigation. Studies suggest it may be effective for pain relief, reducing drug use, and managing withdrawal symptoms. However, the research is limited and mainly observational.

  • The Pharmacology and Toxicology of Kratom: from Traditional Herb to Drug of Abuse

    While touted for mood-boosting, pain relief, and even opiate withdrawal help, kratom's safety is unclear. Research suggests both stimulating and sedating effects depending on the dose. National and international attention is rising due to increased hospital visits and deaths potentially linked to kratom use.

  • Kratom (Mitragyna speciosa): User Demographics, Use Patterns, and Implications for the Opioid Epidemic

    Kratom, a Southeast Asian plant with opioid-receptor mediated effects, has emerged as a potential substance of abuse, with limited data on its use and effects. This study characterized kratom user demographics, use patterns, and perceived drug effects.

  • Kratom Use and Toxicities in the United States

    Kratom is an herbal supplement containing alkaloids with opioid properties. This review was conducted to determine toxicities associated with kratom use in the United States in order to provide insight into its safety as a dietary supplement

  • A Case of Severe Kratom Addiction Contributing to a Suicide Attempt

    Kratom's risks are largely unknown, and the market is poorly regulated. These risks are highlighted in this case of a 38-year-old woman with a history of major depressive disorder and opioid use disorder who switched from Suboxone to kratom and became addicted, eventually consuming large quantities per day.